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ZDHC3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ZDHC3 Antibody (N-term) AP16170a
    ZDHC3 Antibody (N-term) (Cat. #AP16170a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ZDHC3 antibody detected the ZDHC3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9NYG2
Other Accession NP_057682.1, NP_001128651.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34170 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 51304
Other Names Palmitoyltransferase ZDHHC3, Protein DHHC1, Zinc finger DHHC domain-containing protein 3, DHHC-3, Zinc finger protein 373, ZDHHC3, ZNF373
Target/Specificity This ZDHC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ZDHC3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZDHC3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZDHHC3 (HGNC:18470)
Function Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25.
Cellular Location Golgi apparatus membrane {ECO:0000250|UniProtKB:Q8R173}; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi (By similarity).

References

Hines, R.M., et al. J. Biol. Chem. 285(7):4621-4628(2010)
Lim, J., et al. Cell 125(4):801-814(2006)
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Uemura, T., et al. Biochem. Biophys. Res. Commun. 296(2):492-496(2002)

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$ 295.00
$ 99.00
Cat# AP16170a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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