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LINGO3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LINGO3 Antibody (C-term) AP16177b
    LINGO3 Antibody (C-term) (Cat. #AP16177b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the LINGO3 antibody detected the LINGO3 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P0C6S8
Other Accession NP_001094861.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 395-424 aa
Additional Information
Other Names Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3, Leucine-rich repeat neuronal protein 2, Leucine-rich repeat neuronal protein 6B, LINGO3, LERN2, LRRN6B
Target/Specificity This LINGO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the C-terminal region of human LINGO3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLINGO3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LINGO3
Synonyms LERN2, LRRN6B
Cellular Location Membrane; Single-pass type I membrane protein EMBL; AC004152; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS45905.1; - RefSeq; NP_001094861.1; NM_001101391.1 UniGene; Hs.371587; - ProteinModelPortal; P0C6S8; - SMR; P0C6S8; - STRING; 9606.ENSP00000384979; - PhosphoSitePlus; P0C6S8; - BioMuta; LINGO3; - DMDM; 182662399; - PaxDb; P0C6S8; - PeptideAtlas; P0C6S8; - PRIDE; P0C6S8; - ProteomicsDB; 52330; - Ensembl; ENST00000585527; ENSP00000467753; ENSG00000220008 GeneID; 645191; - KEGG; hsa:645191; - UCSC; uc060rka.1; human CTD; 645191; - EuPathDB; HostDB:ENSG00000220008.3; - GeneCards; LINGO3; - H-InvDB; HIX0202769; - HGNC; HGNC:21206; LINGO3 HPA; HPA043781; - HPA; HPA055932; - HPA; HPA059558; - MIM; 609792; gene neXtProt; NX_P0C6S8; - OpenTargets; ENSG00000220008; - PharmGKB; PA162394097; - eggNOG; KOG0619; Eukaryota eggNOG; COG4886; LUCA GeneTree; ENSGT00760000118831; - HOGENOM; HOG000246971; - HOVERGEN; HBG057546; - InParanoid; P0C6S8; - OMA; VSFLCRA; - OrthoDB; EOG091G047N; - PhylomeDB; P0C6S8; - TreeFam; TF334360; - GenomeRNAi; 645191; - PRO; PR:P0C6S8; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000220008; - CleanEx; HS_LINGO3; - Genevisible; P0C6S8; HS GO; GO:0005615; C:extracellular space; IBA:GO_Central GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW Gene3D; 2.60.40.10; -; 1 Gene3D; 3.80.10.10; -; 1 InterPro; IPR000483; Cys-rich_flank_reg_C InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR013098; Ig_I-set InterPro; IPR003599; Ig_sub InterPro; IPR003598; Ig_sub2 InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf InterPro; IPR000372; LRRNT Pfam; PF07679; I-set; 1 Pfam; PF13855; LRR_8; 3 SMART; SM00409; IG; 1 SMART; SM00408; IGc2; 1 SMART; SM00369; LRR_TYP; 9 SMART; SM00082; LRRCT; 1 SMART; SM00013; LRRNT; 1 SUPFAM; SSF48726; SSF48726; 1 PROSITE; PS50835; IG_LIKE; 1 PROSITE; PS51450; LRR; 7 3: Inferred from homology; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Leucine-rich repeat; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 24 CHAIN 25 592 Leucine-rich repeat and immunoglobulin- like domain-containing nogo receptor- interacting protein 3 /FTId=PRO_0000326529 TOPO_DOM 25 531 Extracellular. TRANSMEM 532 552 Helical. TOPO_DOM 553 592 Cytoplasmic. DOMAIN 25 54 LRRNT REPEAT 55 76 LRR 1 REPEAT 79 100 LRR 2 REPEAT 103 124 LRR 3 REPEAT 127 148 LRR 4 REPEAT 151 172 LRR 5 REPEAT 175 196 LRR 6 REPEAT 207 228 LRR 7 REPEAT 247 268 LRR 8 REPEAT 271 292 LRR 9 REPEAT 295 316 LRR 10 REPEAT 319 340 LRR 11 DOMAIN 352 406 LRRCT DOMAIN 407 496 Ig-like C2-type COMPBIAS 576 579 Poly-Ala CARBOHYD 127 127 N-linked (GlcNAc...) asparagine CARBOHYD 185 185 N-linked (GlcNAc...) asparagine CARBOHYD 247 247 N-linked (GlcNAc...) asparagine CARBOHYD 257 257 N-linked (GlcNAc...) asparagine CARBOHYD 276 276 N-linked (GlcNAc...) asparagine CARBOHYD 324 324 N-linked (GlcNAc...) asparagine CARBOHYD 488 488 N-linked (GlcNAc...) asparagine CARBOHYD 512 512 N-linked (GlcNAc...) asparagine DISULFID 429 480 {ECO:0000255|PROSITE-ProRule:PRU00114} VARIANT 426 426 R -> H (in dbSNP:rs7258841) /FTId=VAR_059395 SEQUENCE 592 AA; 64881 MW; 54C12AD313CE1414 CRC64; MTCWLCVLSL PLLLLPAAPP PAGGCPARCE CTVQTRAVAC TRRRLTAVPD GIPAETRLLE LSRNRIRCLN PGDLAALPAL EELDLSENAI AHVEPGAFAN LPRLRVLRLR GNQLKLIPPG VFTRLDNLTL LDLSENKLVI LLDYTFQDLH SLRRLEVGDN DLVFVSRRAF AGLLALEELT LERCNLTALS GESLGHLRSL GALRLRHLAI ASLEDQNFRR LPGLLHLEID NWPLLEEVAA GSLRGLNLTS LSVTHTNITA VPAAALRHQA HLTCLNLSHN PISTVPRGSF RDLVRLRELH LAGALLAVVE PQAFLGLRQI RLLNLSNNLL STLEESTFHS VNTLETLRVD GNPLACDCRL LWIVQRRKTL NFDGRLPACA TPAEVRGDAL RNLPDSVLFE YFVCRKPKIR ERRLQRVTAT AGEDVRFLCR AEGEPAPTVA WVTPQHRPVT ATSAGRARVL PGGTLEIQDA RPQDSGTYTC VASNAGGNDT YFATLTVRPE PAANRTPGEA HNETLAALRA PLDLTTILVS TAMGCITFLG VVLFCFVLLF VWSRGRGQHK NNFSVEYSFR KVDGPAAAAG QGGARKFNMK MI
Research Areas
Citations (0)

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References

Carim-Todd, L., et al. Eur. J. Neurosci. 18(12):3167-3182(2003)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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$ 295.00
$ 99.00
Cat# AP16177b
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(40 western blots)
Availability: In Stock
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