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C1RL Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9NZP8 |
| Other Accession | NP_057630.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 53498 Da |
| Antigen Region | 161-190 aa |
| Gene ID | 51279 |
|---|---|
| Other Names | Complement C1r subcomponent-like protein, C1r-LP, C1r-like protein, 3421-, C1r-like serine protease analog protein, CLSPa, C1RL, C1RL1, C1RLP, CLSPA |
| Target/Specificity | This C1RL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the Central region of human C1RL. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C1RL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | C1RL |
|---|---|
| Synonyms | C1RL1, C1RLP, CLSPA |
| Function | Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. |
| Cellular Location | Secreted. |
| Tissue Location | Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U-251MG (glioma) or A-549 (lung carcinoma) cells Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level) |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
C1RL mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.
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$ 365.00
$ 140.00
Cat# AP16193c
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