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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   RNF160 Antibody (Center)   

RNF160 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RNF160 Antibody (Center) AP16206c
    RNF160 Antibody (Center) (Cat. #AP16206c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the RNF160 antibody detected the RNF160 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94822
Other Accession NP_056380.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 200552 Da
Antigen Region 1087-1115 aa
Additional Information
Gene ID 26046
Other Names E3 ubiquitin-protein ligase listerin, 632-, RING finger protein 160, Zinc finger protein 294, LTN1, C21orf10, C21orf98, KIAA0714, RNF160, ZNF294
Target/Specificity This RNF160 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1087-1115 amino acids from the Central region of human RNF160.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRNF160 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTN1
Synonyms C21orf10, C21orf98, KIAA0714, RNF160, ZN
Function E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:23685075, PubMed:25132172, PubMed:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity).
Research Areas
Citations (0)

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Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM].


Bengtson, M.H., et al. Nature 467(7314):470-473(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Chu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(7):2097-2103(2009)

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Cat# AP16206c
(40 western blots)
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