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LIM2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LIM2 Antibody (C-term) AP16239b
    LIM2 Antibody (C-term) (Cat. #AP16239b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the LIM2 antibody detected the LIM2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P55344
Other Accession P54825, P56563, P20274, NP_085915.2, NP_001155220.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 19674 Da
Antigen Region 110-137 aa
Additional Information
Gene ID 3982
Other Names Lens fiber membrane intrinsic protein, MP18, MP19, MP20, LIM2
Target/Specificity This LIM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-137 amino acids from the C-terminal region of human LIM2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLIM2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIM2
Function Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Eye lens specific..
Research Areas
Citations (0)
citation

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Background

LIM2 is an eye lens-specific protein found at the junctions of lens fiber cells, where it may contribute to cell junctional organization. It acts as a receptor for calmodulin, and may play an important role in both lens development and cataractogenesis. Mutations in this gene have been associated with cataract formation.

References

Ponnam, S.P., et al. Mol. Vis. 14, 1204-1208 (2008) :
Hsu, H., et al. Sheng Wu Gong Cheng Xue Bao 20(4):507-515(2004)
Wistow, G., et al. Mol. Vis. 8, 171-184 (2002) :
Wistow, G., et al. Mol. Vis. 8, 185-195 (2002) :
Pras, E., et al. Am. J. Hum. Genet. 70(5):1363-1367(2002)

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$ 365.00
$ 140.00
Cat# AP16239b
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