|Application ||WB, E|
|Other Accession||P20615, NP_076922.1|
|Calculated MW||28059 Da|
|Antigen Region||148-176 aa|
|Other Names||Homeobox protein Hox-B9, Homeobox protein Hox-25, Homeobox protein Hox-2E, HOXB9, HOX2E|
|Target/Specificity||This HOXB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of human HOXB9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HOXB9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.|
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Provided below are standard protocols that you may find useful for product applications.
HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
Hayashida, T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(3):1100-1105(2010)
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
Rouault, K., et al. Osteoarthr. Cartil. 17(8):1099-1105(2009)
Nguyen, D.X., et al. Cell 138(1):51-62(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
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