|Application ||WB, E|
|Calculated MW||115272 Da|
|Antigen Region||92-120 aa|
|Other Names||Zinc finger protein 217, ZNF217, ZABC1|
|Target/Specificity||This ZNF217 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human ZNF217.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF217 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.|
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Provided below are standard protocols that you may find useful for product applications.
ZNF217 binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at 'Ser-473'.
Krig, S.R., et al. Oncogene 29(40):5500-5510(2010)
Plevova, P., et al. Neoplasma 57(4):325-332(2010)
Sun, G.Q., et al. Nan Fang Yi Ke Da Xue Xue Bao 29(4):685-688(2009)
Banck, M.S., et al. Epigenetics 4(2):100-106(2009)
Thillainadesan, G., et al. Mol. Cell. Biol. 28(19):6066-6077(2008)
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