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TRAPPC2 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP16270a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16270a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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TRAPPC2 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P0DI81 |
| Other Accession | F1SRI0, Q9CQP2, Q08CN0, Q5ZKP4, Q3T0F2, P0DI82 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Mouse, Pig, Zebrafish |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 16445 Da |
TRAPPC2 Antibody (N-term) - Additional info | |
| Gene ID 6399 | |
| Other Names TRAPPC2; SEDL; Trafficking protein particle complex subunit 2; Sedlin | |
| Target/Specificity This TRAPPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human TRAPPC2. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions TRAPPC2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
TRAPPC2 Antibody (N-term) - Protein Information | |
| Name TRAPPC2 | |
| Synonyms SEDL | |
| Function Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi | |
| Cellular Location Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Localized in perinuclear granular structures | |
| Tissue Location Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes | |
TRAPPC2 Antibody (N-term) - Related products
AP16270a: TRAPPC2 Antibody (N-term)
TRAPPC2 Antibody (N-term) - Application data
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TRAPPC2 Antibody (N-term) (Cat. #AP16270a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TRAPPC2 antibody detected the TRAPPC2 protein (arrow).
TRAPPC2 Antibody (N-term) - Research Areas
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BACKGROUND
TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y.
REFERENCES
Liu, X., et al. J. Cell. Biochem. 109(6):1129-1133(2010) Jeyabalan, J., et al. PLoS ONE 5 (5), E10646 (2010) : Xia, X.Y., et al. Clin. Chim. Acta 410 (1-2), 39-42 (2009) : Guo, H., et al. J. Genet. 88(1):87-91(2009) Xiong, F., et al. Eur. J. Hum. Genet. 17(4):510-516(2009)