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TRAPPC2 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP16270a 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP16270a-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
  • Specification
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  • Reviews
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  • Backgrounds

TRAPPC2 Antibody (N-term) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP0DI81
Other AccessionF1SRI0, Q9CQP2, Q08CN0, Q5ZKP4, Q3T0F2, P0DI82
ReactivityHuman
PredictedBovine, Chicken, Mouse, Pig, Zebrafish
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW16445 Da

TRAPPC2 Antibody (N-term) - Additional info

Gene ID 6399
Other Names
TRAPPC2; SEDL; Trafficking protein particle complex subunit 2; Sedlin
Target/Specificity
This TRAPPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human TRAPPC2.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
TRAPPC2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.

TRAPPC2 Antibody (N-term) - Protein Information

Name TRAPPC2
Synonyms SEDL
Function
Prevents transcriptional repression and induction of cell death by ENO1 (By similarity). May play a role in vesicular transport from endoplasmic reticulum to Golgi
Cellular Location
Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Localized in perinuclear granular structures
Tissue Location
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, fetal cartilage, fibroblasts, placenta and lymphocytes

TRAPPC2 Antibody (N-term) - Related products

AP16270a: TRAPPC2 Antibody (N-term)

RI15443: TRAPPC2 predesign siRNA

AT4333a: TRAPPC2 Antibody (monoclonal) (M01)

TRAPPC2 Antibody (N-term) - Application data

  • TRAPPC2 Antibody (N-term) (Cat. #AP16270a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TRAPPC2 antibody detected the TRAPPC2 protein (arrow).

TRAPPC2 Antibody (N-term) - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

TRAPPC2 is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y.

REFERENCES

Liu, X., et al. J. Cell. Biochem. 109(6):1129-1133(2010) Jeyabalan, J., et al. PLoS ONE 5 (5), E10646 (2010) : Xia, X.Y., et al. Clin. Chim. Acta 410 (1-2), 39-42 (2009) : Guo, H., et al. J. Genet. 88(1):87-91(2009) Xiong, F., et al. Eur. J. Hum. Genet. 17(4):510-516(2009)