|Application ||WB, E|
|Other Accession||NP_001128720.1, NP_002394.1|
|Calculated MW||20826 Da|
|Antigen Region||23-52 aa|
|Other Names||Microfibrillar-associated protein 2, MFAP-2, Microfibril-associated glycoprotein 1, MAGP, MAGP-1, MFAP2, MAGP1|
|Target/Specificity||This MFAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-52 amino acids from the N-terminal region of human MFAP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MFAP2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the elastin-associated microfibrils.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
Microfibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene.
Krumbiegel, M., et al. Invest. Ophthalmol. Vis. Sci. 50(6):2796-2801(2009)
Segade, F., et al. Int. J. Biochem. Cell Biol. 39(12):2303-2313(2007)
Miyamoto, A., et al. J. Biol. Chem. 281(15):10089-10097(2006)
Clarke, A.W., et al. Eur. J. Biochem. 271(14):3085-3090(2004)
Werneck, C.C., et al. J. Biol. Chem. 279(22):23045-23051(2004)
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