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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MOCS2 Antibody (N-term)   

MOCS2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MOCS2 Antibody (N-term) AP16279a
    MOCS2 Antibody (N-term) (Cat. #AP16279a) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the MOCS2 antibody detected the MOCS2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O96007
Other Accession NP_004522.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20944 Da
Antigen Region 14-43 aa
Additional Information
Gene ID 4338
Other Names Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052}, 28112 {ECO:0000255|HAMAP-Rule:MF_03052}, MOCO1-B, Molybdenum cofactor synthesis protein 2 large subunit {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdenum cofactor synthesis protein 2B {ECO:0000255|HAMAP-Rule:MF_03052}, MOCS2B {ECO:0000255|HAMAP-Rule:MF_03052}, Molybdopterin-synthase large subunit, MPT synthase large subunit, MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}, MCBPE, MOCO1
Target/Specificity This MOCS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human MOCS2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMOCS2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MOCS2 {ECO:0000255|HAMAP-Rule:MF_03052}
Synonyms MCBPE, MOCO1
Function Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
Cellular Location Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03052, ECO:0000269|PubMed:15073332}
Tissue Location Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas Very low levels are found in lung and peripheral blood leukocytes
Research Areas
Citations (0)

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Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits.


Per, H., et al. Brain Dev. 29(6):365-368(2007)
Hahnewald, R., et al. Mol. Genet. Metab. 89(3):210-213(2006)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Leimkuhler, S., et al. Hum. Genet. 117(6):565-570(2005)
Matthies, A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(16):5946-5951(2004)

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$ 295.00
$ 99.00
Cat# AP16279a
(40 western blots)
Availability: In Stock
Bulk Size
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