|Application ||WB, E|
|Calculated MW||59633 Da|
|Antigen Region||344-373 aa|
|Other Names||Butyrophilin subfamily 2 member A1, BTN2A1, BT21, BTF1|
|Target/Specificity||This BTN2A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human BTN2A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BTN2A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
BTN2A1 is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
Malcherek, G., et al. J. Immunol. 179(6):3804-3811(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Mungall, A.J., et al. Nature 425(6960):805-811(2003)
Rhodes, D.A., et al. Genomics 71(3):351-362(2001)
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