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PAP2D Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PAP2D Antibody (Center) AP16291c
    PAP2D Antibody (Center) (Cat. #AP16291c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PAP2D antibody detected the PAP2D protein (arrow).
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q32ZL2
Other Accession Q8BJ52, NP_001010861.1, NP_001032394.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35427 Da
Antigen Region 78-106 aa
Additional Information
Gene ID 163404
Other Names Lipid phosphate phosphatase-related protein type 5, 313-, Phosphatidic acid phosphatase 2d, Plasticity-related gene 5 protein, PRG-5, LPPR5, PAP2D
Target/Specificity This PAP2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human PAP2D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAP2D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLPPR5 (HGNC:31703)
Function Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retraction.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q8BJ52}; Multi-pass membrane protein
Tissue Location Isoform 1 is expressed in brain, lung, kidney and colon. Isoform 2 is expressed in placenta, skeletal muscle and kidney
Research Areas
Citations (0)
citation

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Background

PAP2D is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Broggini, T., et al. Mol. Biol. Cell 21(4):521-537(2010)
Sun, L., et al. Mol. Cell. Biochem. 272 (1-2), 91-96 (2005) :

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$ 182.50
$ 70.00
Cat# AP16291c
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