|Application ||WB, E|
|Other Accession||Q8BJ52, NP_001010861.1, NP_001032394.1|
|Calculated MW||35427 Da|
|Antigen Region||78-106 aa|
|Other Names||Lipid phosphate phosphatase-related protein type 5, 313-, Phosphatidic acid phosphatase 2d, Plasticity-related gene 5 protein, PRG-5, LPPR5, PAP2D|
|Target/Specificity||This PAP2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-106 amino acids from the Central region of human PAP2D.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAP2D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Isoform 1 is expressed in brain, lung, kidney and colon. Isoform 2 is expressed in placenta, skeletal muscle and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
PAP2D is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Broggini, T., et al. Mol. Biol. Cell 21(4):521-537(2010)
Sun, L., et al. Mol. Cell. Biochem. 272 (1-2), 91-96 (2005) :
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