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HIST2H2BF Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HIST2H2BF Antibody (N-term) AP16318a
    HIST2H2BF Antibody (N-term) (Cat. #AP16318a) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST2H2BF antibody detected the HIST2H2BF protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q5QNW6
Other Accession P57053, Q64525, P62808, Q8CGP2, Q99877, Q32L48, P10854, Q99879, Q99880, Q8CGP1, Q2PFX4, O60814, Q2M2T1, Q64478, Q93079, P10853, P58876, Q6ZWY9, P62807, Q64475, NP_001019770.1
Reactivity Human
Predicted Mouse, Bovine, Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13920 Da
Antigen Region 14-42 aa
Additional Information
Gene ID 440689
Other Names Histone H2B type 2-F, HIST2H2BF
Target/Specificity This HIST2H2BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human HIST2H2BF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIST2H2BF Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HIST2H2BF
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular Location Nucleus. Chromosome.
Citations (0)

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Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

References

Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Pavri, R., et al. Cell 125(4):703-717(2006)
Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)
Zhu, B., et al. Mol. Cell 20(4):601-611(2005)
Golebiowski, F., et al. Mol. Cell. Biochem. 279 (1-2), 133-139 (2005) :

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$ 295.00
$ 99.00
Cat# AP16318a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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