|Application ||WB, E|
|Calculated MW||42344 Da|
|Antigen Region||320-348 aa|
|Other Names||Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2, STK17B, DRAK2|
|Target/Specificity||This STK17B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-348 amino acids from the C-terminal region of human STK17B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STK17B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.|
|Cellular Location||Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.|
|Tissue Location||Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
STK17B acts as a positive regulator of apoptosis.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Doherty, G.A., et al. Br. J. Cancer 101(3):483-491(2009)
Gatzka, M., et al. J. Immunol. 183(1):285-297(2009)
Friedrich, M.L., et al. J. Biol. Chem. 282(7):4573-4584(2007)
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