|Application ||WB, E|
|Calculated MW||42344 Da|
|Antigen Region||320-348 aa|
|Other Names||Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2, STK17B, DRAK2|
|Target/Specificity||This STK17B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-348 amino acids from the C-terminal region of human STK17B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STK17B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.|
|Cellular Location||Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.|
|Tissue Location||Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney|
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Provided below are standard protocols that you may find useful for product applications.
STK17B acts as a positive regulator of apoptosis.
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Landa, I., et al. PLoS Genet. 5 (9), E1000637 (2009) :
Doherty, G.A., et al. Br. J. Cancer 101(3):483-491(2009)
Gatzka, M., et al. J. Immunol. 183(1):285-297(2009)
Friedrich, M.L., et al. J. Biol. Chem. 282(7):4573-4584(2007)
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