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ELOVL4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ELOVL4 Antibody (C-term) AP16326b
    All lanes : Anti-ELOVL4 Antibody (C-term) at 1:1000 dilution Lane 1: human testis lysate Lane 2: Y79 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 37 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - ELOVL4 Antibody (C-term) AP16326b
    ELOVL4 Antibody (C-term) (Cat. #AP16326b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ELOVL4 antibody detected the ELOVL4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9GZR5
Other Accession Q95K73, NP_073563.1
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36829 Da
Antigen Region 286-314 aa
Additional Information
Gene ID 6785
Other Names Elongation of very long chain fatty acids protein 4, 3-keto acyl-CoA synthase ELOVL4, ELOVL fatty acid elongase 4, ELOVL FA elongase 4, Very-long-chain 3-oxoacyl-CoA synthase 4, ELOVL4
Target/Specificity This ELOVL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human ELOVL4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsELOVL4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May play a critical role in early brain and skin development.
Cellular Location Endoplasmic reticulum membrane; Multi- pass membrane protein
Tissue Location Expressed in the retina and at much lower level in the brain. Ubiquitous, highest expression in thymus, followed by testis, small intestine, ovary, and prostate. Little or no expression in heart, lung, liver, or leukocates
Research Areas
Citations (0)

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ELOVL4 is a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration.


Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :
Vasireddy, V., et al. Prog Retin Eye Res 29(3):191-207(2010)
Gu, H., et al. Zhonghua Yan Ke Za Zhi 46(2):125-128(2010)
DeAngelis, M.M., et al. Arch. Ophthalmol. 125(1):49-54(2007)
McMahon, A., et al. Mol. Vis. 13, 258-272 (2007) :

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$ 295.00
$ 99.00
Cat# AP16326b
(40 western blots)
Availability: In Stock
Bulk Size
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