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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RASD2 Antibody (Center)   

RASD2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RASD2 Antibody (Center) AP16330c
    RASD2 Antibody (Center) (Cat. #AP16330c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RASD2 antibody detected the RASD2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96D21
Other Accession NP_055125.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30366 Da
Antigen Region 86-114 aa
Additional Information
Gene ID 23551
Other Names GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2, RASD2, TEM2
Target/Specificity This RASD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human RASD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRASD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASD2
Synonyms TEM2
Function GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.
Cellular Location Cell membrane; Lipid-anchor
Tissue Location Pancreatic endocrine cells (islets of Langerhans).
Research Areas
Citations (0)

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Background

RASD2 is a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades.

References

Hill, C., et al. Cell. Physiol. Biochem. 23 (1-3), 1-8 (2009) :
Liu, Y.L., et al. Biol. Psychiatry 64(9):789-796(2008)
Thapliyal, A., et al. Am. J. Physiol., Cell Physiol. 295 (5), C1417-C1426 (2008) :
Agretti, P., et al. J. Endocrinol. Invest. 30(4):279-284(2007)
Taylor, J.P., et al. Biochem. Biophys. Res. Commun. 349(2):809-815(2006)

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$ 295.00
$ 99.00
Cat# AP16330c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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