ZN673 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q5JUW0 |
Other Accession | NP_001123372.1, NP_001123371.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 20100 Da |
Antigen Region | 96-125 aa |
Gene ID | 55634 |
---|---|
Other Names | KRAB domain-containing protein 4, KRAB box domain-containing protein 4, KRBOX4, ZNF673 |
Target/Specificity | This ZN673 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the C-terminal region of human ZN673. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZN673 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KRBOX4 |
---|---|
Synonyms | ZNF673 |
Tissue Location | Expressed in brain, ovary, testis, prostate, tonsil, heart, bone marrow, colon, breast and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZNF673 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF673 may be involved in transcriptional regulation. Defects in ZNF673 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
References
Lugtenberg, D., et al. Am. J. Hum. Genet. 78(2):265-278(2006)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Thiselton, D.L., et al. Genomics 79(4):560-572(2002)
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