|Application ||WB, E|
|Other Accession||NP_001123372.1, NP_001123371.1|
|Calculated MW||20100 Da|
|Antigen Region||96-125 aa|
|Other Names||KRAB domain-containing protein 4, KRAB box domain-containing protein 4, KRBOX4, ZNF673|
|Target/Specificity||This ZN673 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the C-terminal region of human ZN673.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZN673 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in brain, ovary, testis, prostate, tonsil, heart, bone marrow, colon, breast and kidney|
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Provided below are standard protocols that you may find useful for product applications.
ZNF673 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF673 may be involved in transcriptional regulation. Defects in ZNF673 may be the cause of mental retardation X-linked type 92 (MRX92). Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.
Lugtenberg, D., et al. Am. J. Hum. Genet. 78(2):265-278(2006)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Thiselton, D.L., et al. Genomics 79(4):560-572(2002)
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