Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
CCDC46 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8N8E3 |
| Other Accession | NP_001032402.1, NP_659473.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 112749 Da |
| Antigen Region | 286-314 aa |
| Gene ID | 201134 |
|---|---|
| Other Names | Centrosomal protein of 112 kDa, Cep112, Coiled-coil domain-containing protein 46, CEP112, CCDC46 |
| Target/Specificity | This CCDC46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the N-terminal region of human CCDC46. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CCDC46 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CEP112 |
|---|---|
| Synonyms | CCDC46 |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes around spindle poles in some cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
CCDC46 is a protein with filament, myosin tail and ATPase domains. Orthologs of this gene exist in mouse, rat and chimp. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
References
Mick, E., et al. J Am Acad Child Adolesc Psychiatry 49(9):898-905(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sombekke, M.H., et al. Mult. Scler. 16(6):652-659(2010)
Johansson, A., et al. Obesity (Silver Spring) 18(4):803-808(2010)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
