|Application ||WB, E|
|Other Accession||NP_001032402.1, NP_659473.2|
|Calculated MW||112749 Da|
|Antigen Region||286-314 aa|
|Other Names||Centrosomal protein of 112 kDa, Cep112, Coiled-coil domain-containing protein 46, CEP112, CCDC46|
|Target/Specificity||This CCDC46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the N-terminal region of human CCDC46.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCDC46 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes around spindle poles in some cells.|
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Provided below are standard protocols that you may find useful for product applications.
CCDC46 is a protein with filament, myosin tail and ATPase domains. Orthologs of this gene exist in mouse, rat and chimp. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Mick, E., et al. J Am Acad Child Adolesc Psychiatry 49(9):898-905(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sombekke, M.H., et al. Mult. Scler. 16(6):652-659(2010)
Johansson, A., et al. Obesity (Silver Spring) 18(4):803-808(2010)
Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
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