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ELL2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ELL2 Antibody (C-term) AP16355b
    ELL2 Antibody (C-term) (Cat. #AP16355b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the ELL2 antibody detected the ELL2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00472
Other Accession NP_036213.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 72324 Da
Antigen Region 450-479 aa
Additional Information
Gene ID 22936
Other Names RNA polymerase II elongation factor ELL2, ELL2
Target/Specificity This ELL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human ELL2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsELL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ELL2
Function Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:22195968). Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane- specific to secretory IgH mRNA expression.
Cellular Location Nucleus.
Citations (0)

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Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Martincic, K., et al. Nat. Immunol. 10(10):1102-1109(2009) Simone, F., et al. Blood 101(6):2355-2362(2003) Simone, F., et al. Blood 98(1):201-209(2001) Shilatifard, A., et al. Proc. Natl. Acad. Sci. U.S.A. 94(8):3639-3643(1997)

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$ 295.00
$ 99.00
Cat# AP16355b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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