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CDCP1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDCP1 Antibody (C-term) AP16364B
    CDCP1 Antibody (C-term) (Cat. #AP16364b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDCP1 antibody detected the CDCP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H5V8
Other Accession NP_835488.1, NP_073753.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92932 Da
Antigen Region 704-732 aa
Additional Information
Gene ID 64866
Other Names CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD318, CDCP1, TRASK
Target/Specificity This CDCP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 704-732 amino acids from the C-terminal region of human CDCP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDCP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDCP1
Synonyms TRASK
Function May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Cellular Location Isoform 1: Cell membrane; Single-pass membrane protein. Note=Shedding may also lead to a soluble peptide
Tissue Location Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells
Research Areas
Citations (0)

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CDCP1 is a transmembrane protein containing three extracellular CUB domains. This protein is found to be overexpressed in colon and lung cancers. Its expression level is correlated with the metastatic ability of carcinoma cells. This protein is located on the cell surface. It has been shown to be tyrosine phosphorylated in a cancer cell line. Alternatively spliced transcript variants encoding distinct isoforms have been reported.


He, Y., et al. J. Biol. Chem. 285(34):26162-26173(2010)
Miyazawa, Y., et al. Cancer Res. 70(12):5136-5146(2010)
Mamat, S., et al. Oncol. Rep. 23(5):1221-1227(2010)
Fukuchi, K., et al. Mol. Pharm. 7(1):245-253(2010)
Deryugina, E.I., et al. Mol. Cancer Res. 7(8):1197-1211(2009)

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$ 295.00
$ 99.00
Cat# AP16364B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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