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UBP37 Antibody (N-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
United StatesOrdering Information
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(40 western blots)
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(8 western blots)
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- Citations : 0
UBP37 Antibody (N-term) - Product Information
|Other Accession||F1SRY5, Q8C0R0, F1N5V1, NP_065986.2|
|Predicted||Bovine, Mouse, Pig|
|Calculated MW||110170 Da Da|
|Antigen Region||67-94 aa|
UBP37 Antibody (N-term) - Additional Information
|Gene ID 57695|
Ubiquitin carboxyl-terminal hydrolase 37, Deubiquitinating enzyme 37, Ubiquitin thioesterase 37, Ubiquitin-specific-processing protease 37, USP37, KIAA1594
This UBP37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the N-terminal region of human UBP37.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
UBP37 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
UBP37 Antibody (N-term) - Protein Information
Deubiquitinase that antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'- linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Also mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains in vitro. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2).
Expressed in brain and prostate.
UBP37 Antibody (N-term) - Related Products
UBP37 Antibody (N-term) - Research Areas
UBP37 Antibody (N-term) (Cat. #AP16380a) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the UBP37 antibody detected the UBP37 protein (arrow).
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Provided below are standard protocols that you may find useful for product applications.
Belongs to the peptidase C19 family. Contains 3 UIM (ubiquitin-interacting motif) repeats.
Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)
Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004)