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KIF18A Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KIF18A Antibody (C-term) AP16406b
    KIF18A Antibody (C-term) (Cat. #AP16406b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KIF18A antibody detected the KIF18A protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8NI77
Other Accession NP_112494.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 102281 Da
Antigen Region 644-673 aa
Additional Information
Gene ID 81930
Other Names Kinesin-like protein KIF18A, Marrow stromal KIF18A, MS-KIF18A, KIF18A
Target/Specificity This KIF18A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644-673 amino acids from the C-terminal region of human KIF18A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKIF18A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIF18A
Function Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.
Cellular Location Cell projection, ruffle. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Research Areas
Citations (0)
citation

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Background

KIF18A is a member of the kinesin superfamily of microtubule-associated molecular motors (see MIM 148760) that use hydrolysis of ATP to produce force and movement along microtubules (Luboshits and Benayahu, 2005 [PubMed 15878648]).[supplied by OMIM].

References

Zhang, C., et al. Carcinogenesis 31(9):1676-1684(2010)
Du, Y., et al. Curr. Biol. 20(4):374-380(2010)
Huang, Y., et al. Cell Cycle 8(16):2643-2649(2009)
Zusev, M., et al. J. Cell. Physiol. 217(3):618-625(2008)
Stumpff, J., et al. Dev. Cell 14(2):252-262(2008)

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$ 182.50
$ 70.00
Cat# AP16406b
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