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TBL1XR1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TBL1XR1 Antibody (N-term) AP16411A
    TBL1XR1 Antibody (N-term) (Cat. #AP16411a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TBL1XR1 antibody detected the TBL1XR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BZK7
Other Accession Q8BHJ5, Q7SZM9, NP_078941.2
Reactivity Human
Predicted Xenopus, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55595 Da
Antigen Region 109-137 aa
Additional Information
Gene ID 79718
Other Names F-box-like/WD repeat-containing protein TBL1XR1, Nuclear receptor corepressor/HDAC3 complex subunit TBLR1, TBL1-related protein 1, Transducin beta-like 1X-related protein 1, TBL1XR1, IRA1, TBLR1
Target/Specificity This TBL1XR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the N-terminal region of human TBL1XR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBL1XR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBL1XR1
Synonyms IRA1, TBLR1
Function F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Cellular Location Nucleus.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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TBL1XR1 has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Rothenberg, M.E., et al. Nat. Genet. 42(4):289-291(2010)
Parker, H., et al. Genes Chromosomes Cancer 47(12):1118-1125(2008)
Ishii, S., et al. Proc. Natl. Acad. Sci. U.S.A. 105(11):4179-4184(2008)
Li, J., et al. Nat. Cell Biol. 10(2):160-169(2008)

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$ 295.00
$ 99.00
Cat# AP16411A
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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