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NFS1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NFS1 Antibody (Center) AP16412c
    NFS1 Antibody (Center) (Cat. #AP16412c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NFS1 antibody detected the NFS1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y697
Other Accession Q99P39, Q9Z1J3, NP_066923.3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50196 Da
Antigen Region 121-149 aa
Additional Information
Gene ID 9054
Other Names Cysteine desulfurase, mitochondrial, NFS1, NIFS
Target/Specificity This NFS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human NFS1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNFS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NFS1
Synonyms NIFS
Function Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron- sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor.
Cellular Location Isoform Mitochondrial: Mitochondrion.
Tissue Location Predominantly expressed in heart and skeletal muscle. Also found in brain, liver and pancreas
Research Areas
Citations (0)

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Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.


Naamati, A., et al. J. Biol. Chem. 284(44):30200-30208(2009)
Marelja, Z., et al. J. Biol. Chem. 283(37):25178-25185(2008)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Biederbick, A., et al. Mol. Cell. Biol. 26(15):5675-5687(2006)

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$ 295.00
$ 99.00
Cat# AP16412c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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