ZNF24 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P17028 |
Other Accession | Q7TNK3, Q91VN1, NP_008896.2 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 42155 Da |
Antigen Region | 220-248 aa |
Gene ID | 7572 |
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Other Names | Zinc finger protein 24, Retinoic acid suppression protein A, RSG-A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein KOX17, ZNF24, KOX17, ZNF191, ZSCAN3 |
Target/Specificity | This ZNF24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the Central region of human ZNF24. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZNF24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZNF24 |
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Synonyms | KOX17, ZNF191, ZSCAN3 |
Function | Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00187, ECO:0000269|PubMed:24224020} |
Tissue Location | Expressed in many tissues except in heart. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.
References
Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Li, J., et al. Biochem. Biophys. Res. Commun. 397(2):318-322(2010)
Khalfallah, O., et al. Stem Cells 27(7):1643-1653(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Li, J., et al. BMC Genomics 10, 241 (2009) :
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