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ZNF24 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ZNF24 Antibody (Center) AP16413c
    ZNF24 Antibody (Center) (Cat. #AP16413c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ZNF24 antibody detected the ZNF24 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P17028
Other Accession Q7TNK3, Q91VN1, NP_008896.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42155 Da
Antigen Region 220-248 aa
Additional Information
Gene ID 7572
Other Names Zinc finger protein 24, Retinoic acid suppression protein A, RSG-A, Zinc finger and SCAN domain-containing protein 3, Zinc finger protein 191, Zinc finger protein KOX17, ZNF24, KOX17, ZNF191, ZSCAN3
Target/Specificity This ZNF24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-248 amino acids from the Central region of human ZNF24.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZNF24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF24
Synonyms KOX17, ZNF191, ZSCAN3
Function Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00187, ECO:0000269|PubMed:24224020}
Tissue Location Expressed in many tissues except in heart.
Citations (0)

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Background

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically bind to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.

References

Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Li, J., et al. Biochem. Biophys. Res. Commun. 397(2):318-322(2010)
Khalfallah, O., et al. Stem Cells 27(7):1643-1653(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Li, J., et al. BMC Genomics 10, 241 (2009) :

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$ 295.00
$ 99.00
Cat# AP16413c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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