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RGS8 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RGS8 Antibody (N-term) AP16415a
    RGS8 Antibody (N-term) (Cat. #AP16415a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the RGS8 antibody detected the RGS8 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P57771
Other Accession P49804, Q8BXT1, NP_203131.1, NP_001095920.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20917 Da
Antigen Region 14-43 aa
Additional Information
Gene ID 85397
Other Names Regulator of G-protein signaling 8, RGS8, RGS8
Target/Specificity This RGS8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of human RGS8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRGS8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RGS8
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Preferentially binds to G(o)-alpha and G(i)-alpha-3 (By similarity).
Research Areas
Citations (0)

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RGS8 is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation.


Wang, J., et al. Carcinogenesis 31(10):1755-1761(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Fujii, S., et al. Biochem. Biophys. Res. Commun. 377(1):200-204(2008)
Campbell, D.B., et al. Schizophr. Res. 101 (1-3), 67-75 (2008) :
Lamesch, P., et al. Genomics 89(3):307-315(2007)

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Cat# AP16415a
(40 western blots)
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