|Application ||WB, E|
|Other Accession||Q7ZXC9, P09330, Q9CS42, Q4R4R7, P60892, Q9D7G0, Q4R4U3, P60891, Q2HJ58, P38063, P38620, NP_001034180.1|
|Predicted||Yeast, Bovine, Monkey, Mouse, Rat, Xenopus|
|Calculated MW||34769 Da|
|Antigen Region||77-106 aa|
|Other Names||Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2|
|Target/Specificity||This PRPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 amino acids from the Central region of human PRPS2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRPS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.|
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Provided below are standard protocols that you may find useful for product applications.
PRPS2 is a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
Mannava, S., et al. Cell Cycle 7(15):2392-2400(2008)
Tatibana, M., et al. Adv. Enzyme Regul. 35, 229-249 (1995) :
Dawson, S.J., et al. J. Infect. 24(3):317-320(1992)
Ishizuka, T., et al. Biochim. Biophys. Acta 1130(2):139-148(1992)
Becker, M.A., et al. Genomics 8(3):555-561(1990)
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