|Application ||WB, E|
|Other Accession||NP_695005.1, NP_001006115.1|
|Calculated MW||50236 Da|
|Antigen Region||86-115 aa|
|Other Names||Inositol hexakisphosphate kinase 1, InsP6 kinase 1, Inositol hexaphosphate kinase 1, IP6K1, IHPK1, KIAA0263|
|Target/Specificity||This IP6K1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the N-terminal region of human IP6K1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IP6K1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.|
|Cellular Location||Cytoplasm. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
IP6K1 is a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.
Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)
Padmanabhan, U., et al. J. Biol. Chem. 284(16):10571-10582(2009)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Kamimura, J., et al. J. Hum. Genet. 49(7):360-365(2004)
Saiardi, A., et al. J. Biol. Chem. 276(42):39179-39185(2001)
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