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IP6K1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q92551 |
| Other Accession | NP_695005.1, NP_001006115.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50236 Da |
| Antigen Region | 86-115 aa |
| Gene ID | 9807 |
|---|---|
| Other Names | Inositol hexakisphosphate kinase 1, InsP6 kinase 1, Inositol hexaphosphate kinase 1, IP6K1, IHPK1, KIAA0263 |
| Target/Specificity | This IP6K1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-115 amino acids from the N-terminal region of human IP6K1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IP6K1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IP6K1 |
|---|---|
| Synonyms | IHPK1, KIAA0263 |
| Function | Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. |
| Cellular Location | Cytoplasm. Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
IP6K1 is a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.
References
Morgan, A.R., et al. Hum. Immunol. 71(6):602-609(2010)
Padmanabhan, U., et al. J. Biol. Chem. 284(16):10571-10582(2009)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
Kamimura, J., et al. J. Hum. Genet. 49(7):360-365(2004)
Saiardi, A., et al. J. Biol. Chem. 276(42):39179-39185(2001)
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