|Application ||WB, E|
|Calculated MW||107473 Da|
|Antigen Region||529-558 aa|
|Other Names||Scaffold attachment factor B2, SAF-B2, SAFB2, KIAA0138|
|Target/Specificity||This SAFB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-558 amino acids from the Central region of human SAFB2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SAFB2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SAFB2 binds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
Hammerich-Hille, S., et al. Breast Cancer Res. Treat. 121(2):503-509(2010)
Hammerich-Hille, S., et al. J. Biol. Chem. 285(6):3608-3616(2010)
Tsianou, D., et al. FEBS J. 276(18):5212-5227(2009)
Bergman, A., et al. BMC Med. Genet. 9, 108 (2008) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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