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SNAPC2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - SNAPC2 Antibody (C-term) AP16427b
    SNAPC2 Antibody (C-term) (Cat. #AP16427b) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SNAPC2 antibody detected the SNAPC2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13487
Other Accession NP_003074.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 278-307 aa
Additional Information
Other Names snRNA-activating protein complex subunit 2, SNAPc subunit 2, Proximal sequence element-binding transcription factor subunit delta, PSE-binding factor subunit delta, PTF subunit delta, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit, SNAPC2, SNAP45
Target/Specificity This SNAPC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human SNAPC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNAPC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SNAP45
Function Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Cellular Location Nucleus. EMBL; U44898; AAB06230.1; -; mRNA EMBL; U44755; AAC50359.1; -; mRNA EMBL; AK314878; BAG37393.1; -; mRNA EMBL; CH471139; EAW68957.1; -; Genomic_DNA EMBL; CH471139; EAW68958.1; -; Genomic_DNA EMBL; BC011868; AAH11868.1; -; mRNA CCDS; CCDS12190.1; - PIR; JC6082; JC6082 RefSeq; NP_003074.1; NM_003083.3 UniGene; Hs.631860; - ProteinModelPortal; Q13487; - SMR; Q13487; - BioGrid; 112502; 5 DIP; DIP-505N; - IntAct; Q13487; 1 STRING; 9606.ENSP00000221573; - iPTMnet; Q13487; - PhosphoSitePlus; Q13487; - BioMuta; SNAPC2; - DMDM; 8134714; - EPD; Q13487; - MaxQB; Q13487; - PaxDb; Q13487; - PeptideAtlas; Q13487; - PRIDE; Q13487; - DNASU; 6618; - Ensembl; ENST00000221573; ENSP00000221573; ENSG00000104976 GeneID; 6618; - KEGG; hsa:6618; - UCSC; uc002miw.3; human CTD; 6618; - GeneCards; SNAPC2; - HGNC; HGNC:11135; SNAPC2 HPA; HPA049843; - MIM; 605076; gene neXtProt; NX_Q13487; - OpenTargets; ENSG00000104976; - PharmGKB; PA35983; - eggNOG; ENOG410IX3I; Eukaryota eggNOG; ENOG410YPM6; LUCA GeneTree; ENSGT00390000017407; - HOGENOM; HOG000132929; - HOVERGEN; HBG079198; - InParanoid; Q13487; - KO; K15209; - OMA; VEHMTET; - OrthoDB; EOG091G0O5J; - PhylomeDB; Q13487; - TreeFam; TF336993; - BioCyc; ZFISH:ENSG00000104976-MONOMER; - Reactome; R-HSA-6807505; RNA polymerase II transcribes snRNA genes Reactome; R-HSA-749476; RNA Polymerase III Abortive And Retractive Initiation Reactome; R-HSA-76071; RNA Polymerase III Transcription Initiation From Type 3 Promoter GeneWiki; SNAPC2; - GenomeRNAi; 6618; - PRO; PR:Q13487; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000104976; - CleanEx; HS_SNAPC2; - ExpressionAtlas; Q13487; baseline and differential Genevisible; Q13487; HS GO; GO:0005737; C:cytoplasm; IDA:HPA GO; GO:0005654; C:nucleoplasm; TAS:Reactome GO; GO:0005634; C:nucleus; IDA:HPA GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; TAS:ProtInc GO; GO:0009301; P:snRNA transcription; TAS:ProtInc GO; GO:0042795; P:snRNA transcription from RNA polymerase II promoter; TAS:Reactome GO; GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc GO; GO:0006383; P:transcription from RNA polymerase III promoter; TAS:ProtInc InterPro; IPR021281; SnAPC_su2-like Pfam; PF11035; SnAPC_2_like; 1 1: Evidence at protein level; Complete proteome; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 334 snRNA-activating protein complex subunit 2 /FTId=PRO_0000072020 VARIANT 118 118 L -> V (in dbSNP:rs475002) {ECO:0000269|PubMed:14702039, ECO:0000269|Ref.4} /FTId=VAR_011806 SEQUENCE 334 AA; 35556 MW; 441894AF6E1F4083 CRC64; MKPPPRRRAA PARYLGEVTG PATWSAREKR QLVRLLQARQ GQPEPDATEL ARELRGRSEA EIRVFLQQLK GRVAREAIQK VHPGGLQGPR RREAQPPAPI EVWTDLAEKI TGPLEEALAV AFSQVLTIAA TEPVTLLHSK PPKPTQARGK PLLLSAPGGQ EDPAPEIPSS APAAPSSAPR TPDPAPEKPS ESSAGPSTEE DFAVDFEKIY KYLSSVSRSG RSPELSAAES AVVLDLLMSL PEELPLLPCT ALVEHMTETY LRLTAPQPIP AGGSLGPAAE GDGAGSKAPE ETPPATEKAE HSELKSPWQA AGICPLNPFL VPLELLGRAA TPAR
Research Areas
Citations (0)

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SNAPC2 is a subunit of the snRNA-activating protein complex which is associated with the TATA box-binding protein. The encoded protein is necessary for RNA polymerase II and III dependent small-nuclear RNA gene transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq].


Shanmugam, M., et al. J. Biol. Chem. 283(21):14845-14856(2008)
Emran, F., et al. Gene 377, 96-108 (2006) :
Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
Acierno, J.S. Jr., et al. Genomics 73(2):203-210(2001)
Ma, B., et al. J. Biol. Chem. 276(7):5027-5035(2001)

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$ 295.00
$ 99.00
Cat# AP16427b
(40 western blots)
Availability: In Stock
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