|Application ||WB, E|
|Calculated MW||52963 Da|
|Antigen Region||96-125 aa|
|Other Names||Zinc finger and BTB domain-containing protein 32, FANCC-interacting protein, Fanconi anemia zinc finger protein, Testis zinc finger protein, Zinc finger protein 538, ZBTB32, FAZF, TZFP, ZNF538|
|Target/Specificity||This ZBTB32 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the N-terminal region of human ZBTB32.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZBTB32 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FAZF, TZFP, ZNF538|
|Function||DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity).|
|Cellular Location||Nucleus. Note=Located in nuclear speckles|
|Tissue Location||Predominantly expressed in testis. Some isoforms are ubiquitously expressed|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ZBTB32 is a DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T cells (By similarity).
Stogios, P.J., et al. J. Mol. Biol. 400(5):983-997(2010)
Kaufmann, S., et al. J. Gen. Virol. 91 (PT 6), 1494-1502 (2010) :
Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
Cohn, M.A., et al. Mol. Cell 28(5):786-797(2007)
Ikeda, R., et al. J. Cell. Biochem. 101(1):147-154(2007)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.