|Application ||WB, E|
|Other Accession||P56223, NP_002693.3|
|Calculated MW||32645 Da|
|Antigen Region||56-85 aa|
|Other Names||POU domain, class 6, transcription factor 1, Brain-specific homeobox/POU domain protein 5, Brain-5, Brn-5, mPOU homeobox protein, POU6F1, BRN5, MPOU, TCFB1|
|Target/Specificity||This POU6F1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human POU6F1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||POU6F1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRN5, MPOU, TCFB1|
|Function||Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').|
|Tissue Location||In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum|
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Provided below are standard protocols that you may find useful for product applications.
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3') (By similarity).
Suzuki, N., et al. Int. J. Gynecol. Cancer 20(2):212-219(2010)
Yoshioka, N., et al. Hum. Cell 22(4):94-100(2009)
Pereira, J.H., et al. J. Struct. Biol. 167(2):159-165(2009)
Pereira, J.H., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64 (PT 3), 175-178 (2008) :
Abdel-Rahman, B., et al. Hum. Reprod. 10(10):2787-2792(1995)
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