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SLC38A1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16436a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16436a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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SLC38A1 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9H2H9 |
| Other Accession | Q9JM15, Q8K2P7, NP_109599.3, NP_001070952.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 54048 Da |
SLC38A1 Antibody (N-term) - Additional info | |
| Gene ID 81539 | |
| Other Names SLC38A1; ATA1; NAT2; SAT1; SNAT1; Sodium-coupled neutral amino acid transporter 1; Amino acid transporter A1; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1 | |
| Target/Specificity This SLC38A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SLC38A1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SLC38A1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SLC38A1 Antibody (N-term) - Protein Information | |
| Name SLC38A1 | |
| Synonyms ATA1, NAT2, SAT1, SNAT1 | |
| Function Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA | |
| Cellular Location Cell membrane; Multi-pass membrane protein. Note=Restricted to the somatodendritic compartment of neurons Found in the cellular processes of neurons in the developing brain (By similarity) | |
| Tissue Location Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis | |
SLC38A1 Antibody (N-term) - Related products
SLC38A1 Antibody (N-term) - Application data
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SLC38A1 Antibody (N-term) (Cat. #AP16436a) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SLC38A1 antibody detected the SLC38A1 protein (arrow).
SLC38A1 Antibody (N-term) - Research Areas
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BACKGROUND
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).
REFERENCES
Desforges, M., et al. Biochem. Biophys. Res. Commun. 398(1):130-134(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Kim, S., et al. Mol. Psychiatry (2010) In press : Ernst, C., et al. Neuroscience 162(2):415-422(2009) Potkin, S.G., et al. PLoS ONE 4 (8), E6501 (2009) :
