|Application ||WB, E|
|Calculated MW||49180 Da|
|Antigen Region||239-268 aa|
|Other Names||Armadillo repeat-containing X-linked protein 1, ARM protein lost in epithelial cancers on chromosome X 1, Protein ALEX1, ARMCX1, ALEX1|
|Target/Specificity||This ARMCX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human ARMCX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ARMCX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.|
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Provided below are standard protocols that you may find useful for product applications.
ARMCX1 is a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq].
Iseki, H., et al. Cancer Sci. 101(6):1361-1366(2010)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Kurochkin, I.V., et al. Biochem. Biophys. Res. Commun. 280(1):340-347(2001)
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