|Application ||WB, E|
|Other Accession||O88626, O88853, NP_003605.1|
|Calculated MW||39573 Da|
|Antigen Region||279-307 aa|
|Other Names||Galanin receptor type 3, GAL3-R, GALR-3, GALR3, GALNR3|
|Target/Specificity||This GALR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-307 amino acids from the C-terminal region of human GALR3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GALR3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for the hormone galanin. Receptor for the hormone spexin-1 (PubMed:24517231).|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Saus, E., et al. J Psychiatr Res 44(14):971-978(2010)
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :
Belfer, I., et al. Genes Brain Behav. 6(5):473-481(2007)
Berger, A., et al. Neuroendocrinology 75(2):130-138(2002)
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