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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   KBTBD10 Antibody (C-term)   

KBTBD10 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KBTBD10 Antibody (C-term) AP16445b
    KBTBD10 Antibody (C-term) (Cat. #AP16445b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KBTBD10 antibody detected the KBTBD10 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60662
Other Accession Q9ER30, A2AUC9, NP_006054.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68037 Da
Antigen Region 547-575 aa
Additional Information
Gene ID 10324
Other Names Kelch-like protein 41, Kel-like protein 23, Kelch repeat and BTB domain-containing protein 10, Kelch-related protein 1, Sarcosin, KLHL41, KBTBD10, KRP1
Target/Specificity This KBTBD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-575 amino acids from the C-terminal region of human KBTBD10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKBTBD10 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL41
Synonyms KBTBD10, KRP1
Function Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:A2AUC9}. Cell projection, pseudopodium {ECO:0000250|UniProtKB:Q9ER30}. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9ER30}. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250|UniProtKB:A2AUC9} Sarcoplasmic reticulum membrane Endoplasmic reticulum membrane Note=Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation- specific pseudopodia.
Tissue Location Sarcomeric muscle.
Research Areas
Citations (0)

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KBTBD10 is required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.


Foster, L.J., et al. J. Proteome Res. 5(1):64-75(2006)
Lim, D.S., et al. J. Am. Coll. Cardiol. 38(4):1175-1180(2001)
Spence, H.J., et al. Oncogene 19(10):1266-1276(2000)
Taylor, A., et al. Mol. Cell. Biochem. 183 (1-2), 105-112 (1998) :

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$ 295.00
$ 99.00
Cat# AP16445b
(40 western blots)
Availability: In Stock
Bulk Size
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