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CAPN13 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CAPN13 Antibody (C-term) AP16450B
    CAPN13 Antibody (C-term) (Cat. #AP16450b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CAPN13 antibody detected the CAPN13 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q6MZZ7
Other Accession Q3UW68, NP_653176.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 76696 Da
Antigen Region 537-565 aa
Additional Information
Gene ID 92291
Other Names Calpain-13, 3422-, Calcium-activated neutral proteinase 13, CANP 13, CAPN13
Target/Specificity This CAPN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human CAPN13.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCAPN13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAPN13
Function Probable non-lysosomal thiol-protease.
Tissue Location Weakly expressed in lung and testis. Weakly or not expressed in other tissues.
Research Areas
Citations (0)
citation

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Background

Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN13 belongs to the calpain large subunit family.

References

Taylor, J.Y., et al. Biol Res Nurs 12(2):149-155(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Dear, T.N., et al. Gene 274 (1-2), 245-252 (2001) :
Dear, T.N., et al. Genomics 68(2):152-160(2000)

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$ 182.50
$ 70.00
Cat# AP16450B
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