|Application ||WB, E|
|Other Accession||Q3UW68, NP_653176.2|
|Calculated MW||76696 Da|
|Antigen Region||537-565 aa|
|Other Names||Calpain-13, 3422-, Calcium-activated neutral proteinase 13, CANP 13, CAPN13|
|Target/Specificity||This CAPN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 537-565 amino acids from the C-terminal region of human CAPN13.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CAPN13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable non-lysosomal thiol-protease.|
|Tissue Location||Weakly expressed in lung and testis. Weakly or not expressed in other tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN13 belongs to the calpain large subunit family.
Taylor, J.Y., et al. Biol Res Nurs 12(2):149-155(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Dear, T.N., et al. Gene 274 (1-2), 245-252 (2001) :
Dear, T.N., et al. Genomics 68(2):152-160(2000)
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