Mouse Lims2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q91XD2 |
Other Accession | NP_659111.1 |
Reactivity | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39031 Da |
Antigen Region | 296-325 aa |
Gene ID | 225341 |
---|---|
Other Names | LIM and senescent cell antigen-like-containing domain protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, Lims2, Pinch2 |
Target/Specificity | This Mouse Lims2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of mouse Lims2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Lims2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Lims2 |
---|---|
Synonyms | Pinch2 |
Function | Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. |
Cellular Location | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side |
Tissue Location | Detected in heart, lung, kidney, liver, urinary bladder, fat, skin, skeletal muscle, uterus, large intestine and testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration (By similarity).
References
Guo, G., et al. Dev. Cell 18(4):675-685(2010)
Liang, X., et al. Circulation 120(7):568-576(2009)
Pereira, J.A., et al. J. Cell Biol. 185(1):147-161(2009)
Aguado, T., et al. J. Neurosci. 26(5):1551-1561(2006)
Stanchi, F., et al. J. Cell. Sci. 118 (PT 24), 5899-5910 (2005) :
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