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Mouse Lims2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Mouse Lims2 Antibody (C-term) AP16453b
    Mouse Lims2 Antibody (C-term) (Cat. #AP16453b) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Lims2 antibody detected the Lims2 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q91XD2
Other Accession NP_659111.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39031 Da
Antigen Region 296-325 aa
Additional Information
Gene ID 225341
Other Names LIM and senescent cell antigen-like-containing domain protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, Lims2, Pinch2
Target/Specificity This Mouse Lims2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of mouse Lims2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Lims2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Lims2
Synonyms Pinch2
Function Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
Cellular Location Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Detected in heart, lung, kidney, liver, urinary bladder, fat, skin, skeletal muscle, uterus, large intestine and testis.
Research Areas
Citations (0)
citation

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Background

Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration (By similarity).

References

Guo, G., et al. Dev. Cell 18(4):675-685(2010)
Liang, X., et al. Circulation 120(7):568-576(2009)
Pereira, J.A., et al. J. Cell Biol. 185(1):147-161(2009)
Aguado, T., et al. J. Neurosci. 26(5):1551-1561(2006)
Stanchi, F., et al. J. Cell. Sci. 118 (PT 24), 5899-5910 (2005) :

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$ 365.00
$ 140.00
Cat# AP16453b
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