|Application ||WB, E|
|Calculated MW||39031 Da|
|Antigen Region||296-325 aa|
|Other Names||LIM and senescent cell antigen-like-containing domain protein 2, Particularly interesting new Cys-His protein 2, PINCH-2, Lims2, Pinch2|
|Target/Specificity||This Mouse Lims2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the C-terminal region of mouse Lims2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Lims2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.|
|Cellular Location||Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side|
|Tissue Location||Detected in heart, lung, kidney, liver, urinary bladder, fat, skin, skeletal muscle, uterus, large intestine and testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Competes with LIMS1 for binding to ILK. Plays a role in modulating cell spreading and migration (By similarity).
Guo, G., et al. Dev. Cell 18(4):675-685(2010)
Liang, X., et al. Circulation 120(7):568-576(2009)
Pereira, J.A., et al. J. Cell Biol. 185(1):147-161(2009)
Aguado, T., et al. J. Neurosci. 26(5):1551-1561(2006)
Stanchi, F., et al. J. Cell. Sci. 118 (PT 24), 5899-5910 (2005) :
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