Mouse Mesp1 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | P97309 |
Other Accession | O08574, Q0VG99, Q9BRJ9, NP_032614.2 |
Reactivity | Mouse |
Predicted | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 26386 Da |
Antigen Region | 62-91 aa |
Gene ID | 17292 |
---|---|
Other Names | Mesoderm posterior protein 1, Mesp1 |
Target/Specificity | This Mouse Mesp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the Central region of mouse Mesp1. |
Dilution | WB~~1:500-1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Mesp1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Mesp1 |
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Function | Transcription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways. |
Cellular Location | Nucleus. |
Tissue Location | No expression was detected in adult tissues except the testis. Expression in the testis was regulated developmentally; expressed 2 weeks after birth, and increases, reaching the full expression level in mature testes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Mesp1 is a ranscription factor. Plays a role in the epithelialization of somitic mesoderm and in the development of cardiac mesoderm. Defines the rostrocaudal patterning of the somites by participating in distinct Notch pathways.
References
Yu, S., et al. Dev. Biol. 347(1):92-108(2010)
Li, P., et al. Dev. Cell 18(3):480-485(2010)
Powers, S.E., et al. Development 137(2):249-259(2010)
Randall, V., et al. J. Clin. Invest. 119(11):3301-3310(2009)
Dominguez-Frutos, E., et al. Mech. Dev. 126(10):873-881(2009)
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