HOXA13 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P31271 |
Other Accession | Q62424, Q90X25, NP_000513.2 |
Reactivity | Human |
Predicted | Chicken, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39727 Da |
Antigen Region | 356-383 aa |
Gene ID | 3209 |
---|---|
Other Names | Homeobox protein Hox-A13, Homeobox protein Hox-1J, HOXA13, HOX1J |
Target/Specificity | This HOXA13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-383 amino acids from the C-terminal region of human HOXA13. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HOXA13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HOXA13 |
---|---|
Synonyms | HOX1J |
Function | Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.
References
Jorgensen, E.M., et al. Fertil. Steril. 94(4):1235-1238(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Gu, Z.D., et al. Cancer Res. 69(12):4969-4973(2009)
Connell, K.A., et al. Menopause 16(3):529-533(2009)
Yan, W.P., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(1):20-23(2009)
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