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HOXA13 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HOXA13 Antibody (C-term) AP16460b
    HOXA13 Antibody (C-term) (Cat. #AP16460b) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the HOXA13 antibody detected the HOXA13 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P31271
Other Accession Q62424, Q90X25, NP_000513.2
Reactivity Human
Predicted Chicken, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 39727 Da
Antigen Region 356-383 aa
Additional Information
Gene ID 3209
Other Names Homeobox protein Hox-A13, Homeobox protein Hox-1J, HOXA13, HOX1J
Target/Specificity This HOXA13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-383 amino acids from the C-terminal region of human HOXA13.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHOXA13 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXA13
Synonyms HOX1J
Function Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome.

References

Jorgensen, E.M., et al. Fertil. Steril. 94(4):1235-1238(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Gu, Z.D., et al. Cancer Res. 69(12):4969-4973(2009)
Connell, K.A., et al. Menopause 16(3):529-533(2009)
Yan, W.P., et al. Zhonghua Wei Chang Wai Ke Za Zhi 12(1):20-23(2009)

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Discontinued
Cat# AP16460b
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