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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CNTROB Antibody (Center)   

CNTROB Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CNTROB Antibody (Center) AP16471c
    CNTROB Antibody (Center) (Cat. #AP16471c) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CNTROB antibody detected the CNTROB protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N137
Other Accession NP_444279.2.
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 101253 Da
Antigen Region 401-430 aa
Additional Information
Gene ID 116840
Other Names Centrobin, Centrosomal BRCA2-interacting protein, LYST-interacting protein 8, CNTROB, LIP8
Target/Specificity This CNTROB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-430 amino acids from the Central region of human CNTROB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNTROB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms LIP8
Function Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole
Tissue Location Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes
Research Areas
Citations (0)

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CNTROB is a centrosomal protein that interacts with BRCA2 (MIM 600185) and is required for centriole duplication and cytokinesis (Zou et al., 2005 [PubMed 16275750]).[supplied by OMIM].


Lee, J., et al. J. Biol. Chem. 285(33):25476-25484(2010)
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Jeffery, J.M., et al. Oncogene 29(18):2649-2658(2010)
Song, L., et al. Cell. Signal. 22(5):857-864(2010)
Jeong, Y., et al. J. Cell. Sci. 120 (PT 12), 2106-2116 (2007) :

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$ 295.00
$ 99.00
Cat# AP16471c
(40 western blots)
Availability: In Stock
Bulk Size
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