|Application ||WB, E|
|Calculated MW||28296 Da|
|Antigen Region||7-36 aa|
|Other Names||Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2, MYF5, BHLHC2|
|Target/Specificity||This MYF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human MYF5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MYF5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.|
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Provided below are standard protocols that you may find useful for product applications.
MYF5 is involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Venza, M., et al. J. Oral Pathol. Med. 38(1):18-23(2009)
Ansseau, E., et al. PLoS ONE 4 (10), E7482 (2009) :
Kosek, D.J., et al. J. Appl. Physiol. 101(2):531-544(2006)
Summerbell, D., et al. Mech. Dev. 117 (1-2), 331-335 (2002) :
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