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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ADI1 Antibody (Center)   

ADI1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ADI1 Antibody (Center) AP16495c
    ADI1 Antibody (Center) (Cat. #AP16495c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ADI1 antibody detected the ADI1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BV57
Other Accession NP_060739.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21498 Da
Antigen Region 88-116 aa
Additional Information
Gene ID 55256
Other Names 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154}, 1131154 {ECO:0000255|HAMAP-Rule:MF_03154}, Acireductone dioxygenase (Fe(2+)-requiring) {ECO:0000255|HAMAP-Rule:MF_03154}, ARD {ECO:0000255|HAMAP-Rule:MF_03154}, Fe-ARD {ECO:0000255|HAMAP-Rule:MF_03154}, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 {ECO:0000255|HAMAP-Rule:MF_03154}, MTCBP-1 {ECO:0000255|HAMAP-Rule:MF_03154}, Submergence-induced protein-like factor, Sip-L, ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}
Target/Specificity This ADI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-116 amino acids from the Central region of human ADI1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADI1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADI1 {ECO:0000255|HAMAP-Rule:MF_03154}
Function Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
Cellular Location Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14
Tissue Location Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney
Research Areas
Citations (0)

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This gene encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Cheng, J.C., et al. J. Med. Virol. 81(9):1560-1568(2009)
Oram, S.W., et al. Neoplasia 9(8):643-651(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Gotoh, I., et al. Genes Cells 12(1):105-117(2007)

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$ 295.00
$ 99.00
Cat# AP16495c
(40 western blots)
Availability: In Stock
Bulk Size
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