|Application ||WB, E|
|Calculated MW||25038 Da|
|Antigen Region||137-165 aa|
|Other Names||Ras-related protein Rab-41, RAB41|
|Target/Specificity||This RAB41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-165 amino acids from the C-terminal region of human RAB41.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB41 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for normal Golgi ribbon organization and ER-to- Golgi trafficking.|
|Cellular Location||Cytoplasm. Note=punctate localization concentrated in ruffled regions at the cell periphery|
|Tissue Location||Widely expressed in brain, testis, lung, heart, ovary, colon, kidney, uterus and spleen but not in liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a small GTP-binding protein that belongs to the largest family within the Ras superfamily. These proteins function as regulators of membrane trafficking. They cycle between inactive GDP-bound and activated GTP-bound states, which is controlled by GTP hydrolysis-activating proteins (GAPs). This family member can be activated by the GAP protein RN-Tre, and it is localized to the Golgi complex.
Haas, A.K., et al. Nat. Cell Biol. 7(9):887-893(2005)
Pereira-Leal, J.B., et al. J. Mol. Biol. 313(4):889-901(2001)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.