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ADAM23 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ADAM23 Antibody (C-term) AP16502B
    ADAM23 Antibody (C-term) (Cat. #AP16502b) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the ADAM23 antibody detected the ADAM23 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O75077
Other Accession Q9R1V7, NP_003803.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 91926 Da
Antigen Region 803-831 aa
Additional Information
Gene ID 8745
Other Names Disintegrin and metalloproteinase domain-containing protein 23, ADAM 23, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3, MDC-3, ADAM23, MDC3
Target/Specificity This ADAM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 803-831 amino acids from the C-terminal region of human ADAM23.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADAM23 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADAM23
Synonyms MDC3
Function May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in the brain and weakly expressed in the heart. In the brain, expressed prominently in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole.
Research Areas
Citations (0)
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Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.

References

Pan, Q., et al. Biochem. Biophys. Res. Commun. 401(2):306-312(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ferreira, M.A., et al. Allergy 64(11):1623-1628(2009)
Costa, M.D., et al. Neurosci. Lett. 461(1):16-20(2009)
Verbisck, N.V., et al. Cancer Res. 69(13):5546-5552(2009)

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$ 182.50
$ 70.00
Cat# AP16502B
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