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GPKOW Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GPKOW Antibody (Center) AP16513c
    GPKOW Antibody (Center) (Cat. #AP16513c) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the GPKOW antibody detected the GPKOW protein (arrow).
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q92917
Other Accession NP_056513.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52229 Da
Antigen Region 309-338 aa
Additional Information
Gene ID 27238
Other Names G patch domain and KOW motifs-containing protein, G patch domain-containing protein 5, Protein MOS2 homolog, Protein T54, GPKOW, GPATC5, GPATCH5, T54
Target/Specificity This GPKOW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309-338 amino acids from the Central region of human GPKOW.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPKOW Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPKOW
Synonyms GPATC5, GPATCH5, T54
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

T54, also known as GPKOW (G patch domain and KOW motifs), GPATC5 or GPATCH5 (G patch domain-containing protein 5), is a potential RNA-binding protein consisting of one central G patch domain and two C-terminal KOW domains. T54 is a 476 amino acid protein belonging to the MOS2 family. It is a mammalian homolog of the Arabidopsis thaliana MOS2 (modifier of SNC1, 2) nuclear protein that is required for innate immunity. Similar to A. thaliana MOS2, T54 localizes to the nucleus and contains G patch and KOW domains, suggesting that T54 may play a similar role in mammalian innate immunity.

References

Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Zhang, Y., et al. Curr. Biol. 15(21):1936-1942(2005)
Schindelhauer, D., et al. Genome Res. 6(11):1056-1069(1996)

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$ 295.00
$ 99.00
Cat# AP16513c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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