PRSS16 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9NQE7 |
Other Accession | NP_005856.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 55049 Da |
Antigen Region | 52-81 aa |
Gene ID | 10279 |
---|---|
Other Names | Thymus-specific serine protease, 34--, Serine protease 16, PRSS16, TSSP |
Target/Specificity | This PRSS16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human PRSS16. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | PRSS16 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PRSS16 |
---|---|
Synonyms | TSSP |
Function | Protease that may play a role in T-cell development. |
Cellular Location | Cytoplasmic vesicle. Note=Vesicular, either lysosomal or endosomal |
Tissue Location | Expressed predominantly in cortical thymic epithelial cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a serine protease expressed exclusively in the thymus. It is thought to play a role in the alternative antigen presenting pathway used by cortical thymic epithelial cells during the positive selection of T cells. The gene is found in the large histone gene cluster on chromosome 6, near the major histocompatibility complex (MHC) class I region. A second transcript variant has been described, but its full length nature has not been determined.
References
Shi, J., et al. Nature 460(7256):753-757(2009)
Stefansson, H., et al. Nature 460(7256):744-747(2009)
Viken, M.K., et al. Genes Immun. 10(4):323-333(2009)
Lie, B.A., et al. Hum. Immunol. 68(7):592-598(2007)
Luther, C., et al. Genes Immun. 6(1):1-7(2005)
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