|Application ||WB, E|
|Other Accession||P0C6T3, Q3V0I2, NP_085044.2, NP_001167573.1, NP_001167572.1|
|Calculated MW||30930 Da|
|Antigen Region||171-199 aa|
|Other Names||Proline-rich protein 7, Synaptic proline-rich membrane protein, PRR7|
|Target/Specificity||This PRR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human PRR7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRR7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type III membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities (PSD) Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern (By similarity)|
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Provided below are standard protocols that you may find useful for product applications.
Found in a postsynaptic membrane complex with DLG4 and GRIN1. Interacts with DLG4. Interacts preferentially to the PDZ3 domain of DLG4 and to lesser degree to PDZ2 but not to the PDZ1.
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Murata, Y., et al. Biochem. Biophys. Res. Commun. 327(1):183-191(2005)
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