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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CHADL Antibody (Center)   

CHADL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CHADL Antibody (Center) AP16613C
    CHADL Antibody (Center) (Cat. #AP16613c) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the CHADL antibody detected the CHADL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6NUI6
Other Accession NP_612490.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 82388 Da
Antigen Region 406-434 aa
Additional Information
Gene ID 150356
Other Names Chondroadherin-like protein, CHADL, SLRR4B
Target/Specificity This CHADL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the Central region of human CHADL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCHADL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SLRR4B
Function Potential negative modulator of chondrocyte differentiation. Inhibits collagen fibrillogenesis in vitro. May influence chondrocyte's differentiation by acting on its cellular collagenous microenvironment.
Cellular Location Secreted. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:E9Q7T7}
Research Areas
Citations (0)

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Members of the small leucine-rich proteoglycan (SLRP) family are mostly extracellular proteins that function upstream of multiple signaling cascades. They affect intracellular phosphorylation and modulate distinct pathways, such as those driven by Toll-like receptors, TGF? and receptor tyrosine kinases. As a member of the SLRP family, CHADL (Chondroadherin-like protein) is a 762 amino acid protein containing 21 LRR (leucine-rich) repeats, which promote protein-ligand interactions. Chondroadherin, a closely related protein, promotes attachment of chrondocytes, osteoblasts and fibroblasts and also plays an important role in the regulation of chrodrocyte proliferation and growth. CHADL is a secreted protein that is located in the extracellular space. There are two isoforms of CHADL that exist as a result of alternative splicing events.


Barbe, L., et al. Mol. Cell Proteomics 7(3):499-508(2008)

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$ 295.00
$ 99.00
Cat# AP16613C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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