|Application ||WB, E|
|Other Accession||Q6AYB5, P14576, Q4R965, Q2T9U1, NP_003127.1, NP_001139754.1|
|Predicted||Bovine, Monkey, Mouse, Rat|
|Calculated MW||55705 Da|
|Antigen Region||346-374 aa|
|Other Names||Signal recognition particle 54 kDa protein, SRP54, SRP54|
|Target/Specificity||This SRP54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human SRP54.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SRP54 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).|
|Cellular Location||Nucleus speckle. Cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Yoshida, M., et al. Mol. Pharmacol. 73(3):987-994(2008)
Sakashita, E., et al. Mol. Cell. Biol. 24(3):1174-1187(2004)
Kuglstatter, A., et al. Nat. Struct. Biol. 9(10):740-744(2002)
Yin, J., et al. RNA 7(10):1389-1396(2001)
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